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Signal Transduction Cytoskeleton / ECM Extracellular Matrix ECM Proteins Collagen

Recombinant Human COL6A3 protein (His tag) (ab276722)

Recombinant Human COL6A3 protein (His tag) (ab276722)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human COL6A3 protein (His tag)
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P12111
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      TEPLALTETD ICKLPKDEGT CRDFILKWYY DPNTKSCARF WYGGCGGNEN KFGSQKECEK VCAPVLAKPG VISVMGT
    • Predicted molecular weight

      11 kDa including tags
    • Molecular weight information

      The recombinant human COL6A3 comprises 101 amino acids and has a predicted molecular mass of 11.4 kDa. The apparent molecular mass of the protein is approximately 13.3 kDa in SDS-PAGE under reducing conditions.
    • Amino acids

      3101 to 3177
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Predicted N-terminus: His.
  • Specifications

    Our Abpromise guarantee covers the use of ab276722 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • CO6A3_HUMAN
      • COL6A3
      • Collagen alpha-3(VI) chain
      • Collagen type VI alpha 3
      • Collagen VI alpha 3
      see all
    • Function

      Collagen VI acts as a cell-binding protein.
    • Involvement in disease

      Bethlem myopathy 1
      Ullrich congenital muscular dystrophy 1
      Dystonia 27
    • Sequence similarities

      Belongs to the type VI collagen family.
      Contains 1 BPTI/Kunitz inhibitor domain.
      Contains 5 collagen-like domains.
      Contains 1 fibronectin type-III domain.
      Contains 12 VWFA domains.
    • Post-translational
      modifications

      Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
      The N-terminus is blocked.
    • Cellular localization

      Secreted, extracellular space, extracellular matrix.
    • Target information above from: UniProt accession P12111 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant Human COL6A3 protein (ab276722)
    SDS-PAGE - Recombinant Human COL6A3 protein (ab276722)
    SDS-PAGE analysis of ab276722

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276722? Please let us know so that we can cite the reference in this datasheet.

    ab276722 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • CO6A3_HUMAN
    • COL6A3
    • Collagen alpha-3(VI) chain

    Images

    • SDS-PAGE - Recombinant Human COL6A3 protein (ab276722)
      SDS-PAGE - Recombinant Human COL6A3 protein (ab276722)
      SDS-PAGE analysis of ab276722

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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