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Signal Transduction Metabolism Plasma Membrane Channels

Recombinant Human CLIC3 protein (ab185381)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant Human CLIC3 protein
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    O95833
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MAETKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSP DVLKDFAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRE SNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHEL AGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPIPAELR GVRRYLDSAMQEKEFKYTCPHSAEILAAYRPAVHPRLEHHHHHH
    • Predicted molecular weight

      28 kDa including tags
    • Amino acids

      1 to 236
    • Tags

      His tag C-Terminus
  • Associated products

    • Corresponding Antibody

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)
    • Related Products

      • Anti-CLIC3 antibody [EPR8243(B)] (ab128941)
      • Anti-CLIC3 antibody [EPR8244(B)] (ab129186)

    Specifications

    Our Abpromise guarantee covers the use of ab185381 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Additional notes

      Abcam has not and does not intend to apply for the REACH Authorisation of customers’ uses of products that contain European Authorisation list (Annex XIV) substances.
      It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.1% Triton-X-100, 0.121% Tris

      0.2 µM filtered

    General Info

    • Alternative names

      • 2300003G24Rik
      • Chloride intracellular channel 3
      • Chloride intracellular channel protein 3
      • MGC109225
      • OTTHUMP00000022630
      see all
    • Relevance

      Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
    • Cellular localization

      Nuclear, cytoplasmic and Single pass membrane. Predominantly nuclear but also found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab185381? Please let us know so that we can cite the reference in this datasheet.

    ab185381 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Additional notes

      Abcam has not and does not intend to apply for the REACH Authorisation of customers’ uses of products that contain European Authorisation list (Annex XIV) substances.
      It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

    • Concentration information loading...

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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