Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human CHRNB3 protein (His tag) (ab276651)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human CHRNB3 protein (His tag)
    See all CHRNB3 proteins and peptides

  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q05901

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MLPDFMLVLI VLGIPSSATT GFNSIAENED ALLRHLFQGY QKWVRPVLHS NDTIKVYFGL KISQLVDVDE KNQLMTTNVW LKQEWTDHKL RWNPDDYGGI HSIKVPSESL WLPDIVLFEN ADGRFEGSLM TKVIVKSNGT VVWTPPASYK SSCTMDVTFF PFDRQNCSMK FGSWTYDGTM VDLILINENV DRKDFFDNGE WEILNAKGMK GNRRDGVYSY PFITYSFVLR RL

    • Predicted molecular weight

      26 kDa including tags

    • Molecular weight information

      The recombinant human CHRNB3 consists 219 amino acids and predicts a molecular mass of 25.7 kDa.

    • Amino acids

      1 to 232

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Predicted N-terminus: Ile 25.

    • Specifications

    Our Abpromise guarantee covers the use of ab276651 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • AChR
      • Beta-3 subunit precursor
      • CHRNB3
      • Neuronal acetylcholine receptor protein

    • Relevance

      The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.

    • Cellular localization

      Cell Membrane

Images

  • SDS-PAGE - Recombinant Human CHRNB3 protein (ab276651)
    SDS-PAGE - Recombinant Human CHRNB3 protein (ab276651)
    SDS-PAGE analysis of ab276651

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276651? Please let us know so that we can cite the reference in this datasheet.

ab276651 has not yet been referenced specifically in any publications.

Preparation and Storage

  • AChR
  • Beta-3 subunit precursor
  • CHRNB3
  • Neuronal acetylcholine receptor protein

Images

  • SDS-PAGE - Recombinant Human CHRNB3 protein (ab276651)
    SDS-PAGE - Recombinant Human CHRNB3 protein (ab276651)
    SDS-PAGE analysis of ab276651

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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