Recombinant Human Biglycan protein (ab151798)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, HPLC
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -80°C.
pH: 7.20
Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride -
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at
General Info
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Alternative names
- BGN
- Biglycan
- Biglycan proteoglycan
see all -
Function
May be involved in collagen fiber assembly. -
Tissue specificity
Found in several connective tissues, especially in articular cartilages. -
Sequence similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
Contains 12 LRR (leucine-rich) repeats. -
Post-translational
modificationsThe two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate. -
Cellular localization
Secreted > extracellular space > extracellular matrix. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (1)
ab151798 has been referenced in 1 publication.
- Berendsen AD et al. Biglycan modulates angiogenesis and bone formation during fracture healing. Matrix Biol 35:223-31 (2014). PubMed: 24373744
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