Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human ASB13 protein (ab185378)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human ASB13 protein

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. ab185378 is 0.2 µM filtered.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q8WXK3

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MNHKVHHHHHHMEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLI ESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPL CDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDV GANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHA AKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTP LTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN

    • Predicted molecular weight

      31 kDa including tags

    • Amino acids

      1 to 278

    • Tags

      His tag N-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab185378 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 24.02% Urea, 75% PBS

    General Info

    • Alternative names

      • Ankyrin repeat and SOCS box containing 13
      • Ankyrin repeat and SOCS box containing protein 13
      • Ankyrin repeat and SOCS box protein 13
      • Ankyrin repeat domain containing SOCS box protein Asb 13
      • Ankyrin repeat domain containing SOCS box protein Asb13
      • ASB 13
      • ASB-13
      • Asb13
      • ASB13_HUMAN
      • FLJ13134
      • MGC19879
      see all

    • Function

      May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    • Pathway

      Protein modification; protein ubiquitination.

    • Sequence similarities

      Contains 6 ANK repeats.
      Contains 1 SOCS box domain.

    • Domain

      The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185378? Please let us know so that we can cite the reference in this datasheet.

ab185378 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 24.02% Urea, 75% PBS

Images

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