Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human AKR1C2 protein (ab151381)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human AKR1C2 protein

  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Supplied as a 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P52895

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHID SAHVYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDY VDLYLIHFPV SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNH RLLEMILNKP GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDP NSPVLLEDPV LCALAKKHKRTPALIA

    • Predicted molecular weight

      29 kDa

    • Amino acids

      1 to 256

    • Specifications

    Our Abpromise guarantee covers the use of ab151381 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid

    • Additional notes

      Supplied as a 0.2 µM filtered solution.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 0.58% Sodium chloride

    General Info

    • Alternative names

      • 2-dihydrobenzene-1
      • 2-diol dehydrogenase
      • 3 alpha HSD3
      • 3 alpha hydroxysteroid dehydrogenase type III
      • 3-alpha-HSD3
      • AK1C2_HUMAN
      • AKR1C pseudo
      • AKR1C2
      • Aldo keto reductase family 1 member C2
      • Aldo-keto reductase family 1 member C2
      • BABP
      • Bile acid binding protein
      • Chlordecone reductase homolog
      • Chlordecone reductase homolog HAKRD
      • DD
      • DD-2
      • DD/BABP
      • DD2
      • DDH 2
      • DDH2
      • Dihydrodiol dehydrogenase 2
      • Dihydrodiol dehydrogenase/bile acid binding protein
      • Dihydrodiol dehydrogenase/bile acid-binding protein
      • FLJ53800
      • HAKRD
      • HBAB
      • MCDR 2
      • MCDR2
      • OTTHUMP00000044759
      • Pseudo chlordecone reductase
      • SRXY8
      • Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase
      • Trans-1
      • Type II dihydrodiol dehydrogenase
      • Type III 3 alpha hydroxysteroid dehydrogenase
      • Type III 3-alpha-hydroxysteroid dehydrogenase
      see all

    • Function

      Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

    • Sequence similarities

      Belongs to the aldo/keto reductase family.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab151381? Please let us know so that we can cite the reference in this datasheet.

ab151381 has not yet been referenced specifically in any publications.

Preparation and Storage

  • 2-dihydrobenzene-1
  • 2-diol dehydrogenase
  • 3 alpha HSD3

Images

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