QS11, ARFGAP1 inhibitor (ab141408)
Key features and details
- ARFGAP1 inhibitor. Wnt/β-catenin pathway modulator.
- CAS Number: 944328-88-5
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
QS11, ARFGAP1 inhibitor -
Description
ARFGAP1 inhibitor. Wnt/β-catenin pathway modulator. -
Biological description
Potent GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor (EC50 = 0.5 μM). Wnt/β-catenin pathway modulator. Antitumor agent. Active in vitro. -
Purity
> 98% -
CAS Number
944328-88-5 -
Chemical structure
Properties
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Chemical name
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol -
Molecular weight
567.68 -
Molecular formula
C36H33N5O2 -
PubChem identifier
42623900 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)N[C@@H](CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7 -
Source
Synthetic
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Research areas