Purmorphamine, Smoothened receptor agonist (ab120933)
Key features and details
- Smoothened receptor agonist
- CAS Number: 483367-10-8
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Purmorphamine, Smoothened receptor agonist -
Description
Smoothened receptor agonist -
Biological description
Smoothened (Smo) receptor agonist (EC50 ~ 1 μM). Induces osteogenesis in mouse mesenchymal progenitor cells . When combined with BMP-4, can transdifferentiate pre-adipocytes and myoblasts into osteoblasts. Induces differentiation of multipotent mesenchymal progenitor cells into osteoblasts.
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Purity
> 98% -
CAS Number
483367-10-8 -
Chemical structure
Properties
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Chemical name
9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine -
Molecular weight
520.63 -
Molecular formula
C31H32N6O2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O1CCN(CC1)c1ccc(cc1)Nc1nc(Oc2cccc3ccccc23)nc2c1ncn2C1CCCCC1 -
Source
Synthetic
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Research areas