PS48 (DMSO solution), PDK1 activator (ab146626)
Key features and details
- Allosteric PDK1 activator
- CAS Number: 1180678-32-7
- Purity: > 95%
- Supplied in DMSO (10 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
PS48 (DMSO solution), PDK1 activator -
Description
Allosteric PDK1 activator -
Biological description
Allosteric PDK1 activator. Stimulates PI3-kinase and phosphorylates AKT. Binds to the PIF pocket in the small lobe of PDK1. Shows developmental effects in vivo.
Also available as a solid (ab142133). -
Purity
> 95% -
CAS Number
1180678-32-7 -
Chemical structure
Properties
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Chemical name
(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid -
Molecular weight
286.75 -
Molecular formula
C17H15ClO2 -
PubChem identifier
44141940 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (10 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl -
Source
Synthetic
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Research areas
