Phorbol 12-myristate 13-acetate (PMA), PKC activator (DMSO solution) (ab147465)
Key features and details
- PKC activator (DMSO solution)
- CAS Number: 16561-29-8
- Purity: > 99%
- Supplied in DMSO (10mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Phorbol 12-myristate 13-acetate (PMA), PKC activator (DMSO solution) -
Description
PKC activator (DMSO solution) -
Alternative names
- PMA
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Biological description
Potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme activation. Also reported to have actions on non-kinase proteins including chimaerins, RasGRP and Unc-13/Munc-13. Extremely potent mouse skin tumor promoter.
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Purity
> 99% -
CAS Number
16561-29-8 -
Chemical structure
Properties
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Chemical name
Phorbol 12-myristate 13-acetate -
Molecular weight
616.83 -
Molecular formula
C36H56O8 -
PubChem identifier
27924 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Supplied in DMSO (10mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further instruction.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)O[C@@]43[C@H](OC(=O)CCCCCCCCCCCCC)[C@@H](C)[C@@]1(O)[C@@H](C=C(CO)C[C@]2(O)C(=O)C(C)=C[C@@H]12)[C@@H]4C3(C)C -
Source
Synthetic
