PF-04929113 (SNX-5422) (ab273614)
Key features and details
- Potent and selective Hsp90 inhibitor
- CAS Number: 908115-27-5
- Purity: > 99%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PF-04929113 (SNX-5422) -
Description
Potent and selective Hsp90 inhibitor -
Biological description
Potent and selective Hsp90 inhibitor (IC50 = 50 nM). A Her-2 degradation inducer (IC50 = 37 nM).
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Purity
> 99% -
General notes
For obtaining a higher solubility, please warm the tube at 37°C and shake in the ultrasonic bath for a while.
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CAS Number
908115-27-5 -
Chemical structure
Properties
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Chemical name
trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-phenyl]amino)cyclohexyl glycinate
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Molecular weight
521.50 -
Molecular formula
C25H30F3N5O4 -
PubChem identifier
44195571 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 25 mM
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Handling
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C -
Source
Synthetic
Images
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Chemical Structure - PF-04929113 (SNX-5422) (ab273614)
Chemical structure of PF-04929113 (SNX-5422), 908115-27-5