• Product name

  Perilipin-1 peptide
  See all Perilipin-1 proteins and peptides

• Animal free

  No

• Nature

  Synthetic

• Alternative names

  • Lipid droplet associated protein
  • Lipid droplet-associated protein
  • PERI

  • Perilipin
  • Perilipin A
  • Perilipin-1
  • PerilipinA
  • PLIN
  • PLIN1
  • PLIN1_HUMAN

  see all

• Function

  Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.

• Tissue specificity

  Adipocytes.

• Sequence similarities

  Belongs to the perilipin family.

• Post-translational
  modifications

  Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.

• Cellular localization

  Lipid droplet. Lipid droplet surface-associated.

• Target information above from: UniProt accession O60240 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt