PD-1/PD-L1 inhibitor 1, small molecule inhibitor (ab230369)
Key features and details
- Small molecule inhibitor of the PD-1/PD-L1 interaction
- CAS Number: 1675201-83-8
- Purity: > 98%
200 mM in DMSO
200 mM in water
200 mM in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PD-1/PD-L1 inhibitor 1, small molecule inhibitor -
Description
Small molecule inhibitor of the PD-1/PD-L1 interaction -
Alternative names
- Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor 1
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Biological description
PD-1/PD-L1 inhibitor 1 blocks the PD-1/PD-L1 interaction with an IC50 of 6 nM in a cell-free HTRF assay.
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Purity
> 98% -
CAS Number
1675201-83-8 -
Chemical structure
Properties
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Chemical name
(2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylic acid
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Molecular weight
475.86 -
Molecular formula
C29H33NO5 -
PubChem identifier
91663303 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
200 mM in DMSO
200 mM in water
200 mM in ethanol
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SMILES
CC1=C(C=CC=C1COC2=CC(=C(C(=C2)OC)CN3CCCCC3C(=O)O)OC)C4=CC=CC=C4 -
Source
Synthetic
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Research areas
