PACAP (6-27) (human, ovine, rat), receptor antagonist (ab142328)
Key features and details
- Potent, competitive PACAP receptor antagonist. Inhibits stimulation of AC.
- Purity: > 95%
Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
PACAP (6-27) (human, ovine, rat), receptor antagonist -
Description
Potent, competitive PACAP receptor antagonist. Inhibits stimulation of AC. -
Biological description
Potent, competitive PACAP receptor antagonist (Kd = 1 μM). Inhibits stimulation of adenylyl cyclase. Attenuates catecholamine response to exogenous VIP in vivo. Active in vitro and in vivo. -
Purity
> 95% -
Chemical structure
Properties
-
Molecular weight
2638.10 -
Molecular formula
C121H193N33O31S -
Sequence
FTDSYSRYRKQMAVKKYLAAVL (Modifications: C-terminal amide) -
PubChem identifier
16142680 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water
-
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
-
Research areas
