P5091, USP-7 inhibitor (ab144602)
Key features and details
- Potent, selective and cell-permeable USP-7 inhibitor
- CAS Number: 882257-11-6
- Purity: > 98%
- Soluble in DMSO to 50 mM (with warming) and in ethanol to 100 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
P5091, USP-7 inhibitor -
Description
Potent, selective and cell-permeable USP-7 inhibitor -
Biological description
Potent, selective and cell-permeable USP-7 inhibitor (EC50 = 4.2 μM). Induces apoptosis in cancer cells in vitro. Antiangiogenic and antitumor agent. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
882257-11-6 -
Chemical structure
Properties
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Chemical name
1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone -
Molecular weight
348.23 -
Molecular formula
C12H7Cl2NO3S2 -
PubChem identifier
2819993 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM (with warming) and in ethanol to 100 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)C1=CC(=C(S1)SC2=C(C(=CC=C2)Cl)Cl)[N+](=O)[O-] -
Source
Synthetic
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Research areas
