Oligomycin, ATP synthase inhibitor (ab141829)
Key features and details
- ATP synthase inhibitor
- CAS Number: 1404-19-9
- Purity: > 95%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Oligomycin, ATP synthase inhibitor -
Description
ATP synthase inhibitor -
Biological description
ATP synthase inhibitor. Blocks the proton channel (Fo subunit). Macrolide antibiotic. -
Purity
> 95% -
CAS Number
1404-19-9 -
Chemical structure
Properties
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Chemical name
(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29
R)- 22-Ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione (for Oligomycin A) -
Molecular weight
791.07 -
Molecular formula
C45H74O11 (for Oligomycin A) -
PubChem identifier
5281899 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C -
Source
Synthetic
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Research areas
Images
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Functional Studies - Oligomycin, ATP synthase inhibitor (ab141829)Oligomycin inhibits ATP-dependent adipogenesis in 3T3-L1 cells.
Cells were induced to undergo adipocyte differentiation (A-D) for 5 days. Different concentrations of Oligomycin (ab141829) were then added (B, 1 µg/ml; C, 2 µg/ml and D, 10 µg/ml). After 10 days, the cells were stained with Oil Red O and visualized under light microscopy.