Okadaic acid, PP1 and PP2A inhibitor (ab120375)
Key features and details
- PP1 and PP2A inhibitor
- CAS Number: 78111-17-8
- Soluble in DMSO to 100 mM
- Form / State: Solid
Overview
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Product name
Okadaic acid, PP1 and PP2A inhibitor -
Description
PP1 and PP2A inhibitor -
Biological description
Potent inhibitor of protein phosphatase 1 (IC50 = 3 - 15 nM) and protein phosphatase 2A (IC50 = 0.1-1 nM). Highly selective over PP2B, PP2C and a range of other phosphatases. Tumor promotor. -
CAS Number
78111-17-8 -
Chemical structure
Properties
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Chemical name
9,10-Deepithio-9,10-didehydroacanthifolicin -
Molecular weight
805.01 -
Molecular formula
C44H68O13 -
PubChem identifier
446512 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]2CC[C@]1(CCCCO1)O[C@@H]2[C@@H](C)C[C@H](O)[C@H]6O[C@@H]7CC[C@@]3(CC[C@@H](O3)/C=C/[C@@H](C)[C@@H]5CC(C)=C[C@@]4(O[C@@H](CC[C@H]4O)C[C@@](C)(O)C(=O)O)O5)O[C@H]7[C@H](O)C6=C -
Research areas
