NVP-BEZ235, PI3K and mTOR inhibitor (ab120882)
Key features and details
- Potent PI3K and mTOR inhibitor
- CAS Number: 915019-65-7
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
NVP-BEZ235, PI3K and mTOR inhibitor -
Description
Potent PI3K and mTOR inhibitor -
Alternative names
- BEZ-235
- BEZ235
- Dactolisib
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Biological description
Potent, ATP-competitive Phosphatidylinositol 3-
kinase (PI3K) inhibitor (IC50 = 4, 5, 7 and 75 nM for PI3Kα, -γ, -δ, and -β respectively) and mTOR inhibitor. Able to directly induce G1 arrest and inhibit angiogenesis in vitro and potentiate the efficacy of other anticancer agents in vivo. -
Purity
> 98% -
CAS Number
915019-65-7 -
Chemical structure
