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NU 7026, DNA-PK inhibitor (ab120970)

Price and availability

412 099 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Novel, specific, reversible DNA-PK inhibitor
  • CAS Number: 154447-35-5
  • Purity: > 99%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    NU 7026, DNA-PK inhibitor
  • Description

    Novel, specific, reversible DNA-PK inhibitor
  • Biological description

    Novel, specific, reversible DNA-dependent protein kinase (DNA-PK) inhibitor (IC50 = 0.23 μM). Increases G2/M arrest and inhibits double-strand break repair.

  • Purity

    > 99%
  • CAS Number

    154447-35-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one
  • Molecular weight

    281.31
  • Molecular formula

    C17H15NO3
  • PubChem identifier

    9860529
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=C2C=C(Oc1c3ccccc3ccc12)N4CCOCC4
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • Non Homol. End Joining
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • DNA Damage Response
    • DNA Damage Recognition
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • DNA-dependent Protein Kinase

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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