Nefazodone hydrochloride, 5-HT2A antagonist (ab120587)
Key features and details
- Potent 5-HT2A antagonist
- CAS Number: 82752-99-6
- Purity: > 99%
- Soluble in DMSO to 25 mM, in ethanol to 10 mM and in 1 eq. HCl to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Nefazodone hydrochloride, 5-HT2A antagonist -
Description
Potent 5-HT2A antagonist -
Biological description
Potent 5-HT2A receptor antagonist (Ki = 7.1 nM for inhibition of [3H] ketanserin binding in rat cortex). Additionally blocks α1 adrenoceptors (Ki values are 5.5 and 84 nM at α1 and α2, respectively). Acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) (Ki values are 220 and 555 nM at rat SERT and NET, respectively). Antidepressant.
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Purity
> 99% -
CAS Number
82752-99-6 -
Chemical structure
