Native human IgE protein (Azide free) (ab65866)
Key features and details
- Expression system: Native
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, IHC - Wholemount, WB, ELISA, ICC
Preparation and Storage
-
Alternative names
- Igh2
- IGHE
- IGHEP1
- Immunoglobulin heavy constant epsilon
-
Relevance
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock. -
Cellular localization
Cell Membrane