• Product name

  Native Human Apo-H protein
  See all Apo-H proteins and peptides

• Purity

  > 95 % SDS-PAGE.
  Purified using a combination of ion exchange and affinity chromatography.
  

• Expression system

  Native

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Native

• • Species

    Human

• Alternative names

  • Activated protein C binding protein
  • Activated protein C-binding protein
  • Anticardiolipin cofactor

  • APC inhibitor
  • Apo-H
  • APOH
  • APOH_HUMAN
  • Apolipoprotein H
  • apolipoprotein H (beta-2-glycoprotein I)
  • B2G1
  • B2GP1
  • B2GPI
  • Beta 2 glycoprotein I
  • Beta 2 glycoprotein I precursor
  • Beta(2)GPI
  • Beta-2-glycoprotein 1
  • Beta-2-glycoprotein I
  • BG
  • Glycoprotein 1, beta-2
  • Glycoprotein I, beta-2
  • OTTMUSP00000003033

  see all

• Function

  Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

• Tissue specificity

  Expressed by the liver and secreted in plasma.

• Sequence similarities

  Contains 4 Sushi (CCP/SCR) domains.

• Post-translational
  modifications

  N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.

• Cellular localization

  Secreted.

• Target information above from: UniProt accession P02749 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt