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Neuroscience Neurotransmitter Biogenic Amines Dopamine

Nafadotride, D3 antagonist (ab120742)

Price and availability

475 756 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Potent, selective D3 antagonist
  • CAS Number: 149649-22-9
  • Purity: > 99%
  • Soluble in 1eq. HCl to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Nafadotride, D3 antagonist
  • Description

    Potent, selective D3 antagonist
  • Biological description

    Potent, selective D3 antagonist (Ki values are 0.52 nM (D3), 269 nM (D4) and 5 nM (D2)).

  • Purity

    > 99%
  • CAS Number

    149649-22-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide
  • Molecular weight

    365.47
  • Molecular formula

    C22H27N3O2
  • PubChem identifier

    3408722
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1eq. HCl to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCN3CCC[C@H]3CNC(=O)c2cc(C#N)c1ccccc1c2OC
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Potassium Channels
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Dopamine Receptors
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • Heterotrimeric G Proteins
    • G Proteins
    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • Channels
    • Cardiovascular
    • Blood
    • Blood Pressure regulation
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Cardiovascular
    • Vasculature
    • Vasodilation
    • Other
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Dopamine
    • D3
    • Agonists
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Dopamine
    • D3
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Dopamine
    • D3
    • Antagonists
    • Biochemicals
    • Research Area
    • Stress / Anxiety
    • Dopamine
    • D3
    • Antagonists

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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