Mouse IGFBP2 ELISA Kit (ab100691)
Key features and details
- Sensitivity: 0.6 ng/ml
- Range: 0.823 ng/ml - 600 ng/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Mouse
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 500X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml Assay Diluent C 1 x 30ml Biotinylated anti-Mouse IGFBP2 2 vials IGFBP2 Microplate (12 x 8 wells) 1 unit Recombinant Mouse IGFBP2 Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Function
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. -
Sequence similarities
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain. -
Domain
The C-terminus is required for IGF-binding and growth inhibition. -
Post-translational
modificationsO-glycosylated. -
Cellular localization
Secreted. - Information by UniProt
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Alternative names
- BP 2
- BP2
- IBP 2
see all -
Database links
- Entrez Gene: 16008 Mouse
- SwissProt: Q91VK7 Mouse
- SwissProt: P47877 Mouse
- Unigene: 141936 Mouse
Images
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Typical Standard Curve
