Momelotinib (CYT387), ATP-competitve JAK 1/2 selective inhibitor (ab141372)
Key features and details
- Potent ATP-competitve JAK 1/2 selective inhibitor
- CAS Number: 1056634-68-4
- Purity: > 95%
Soluble in DMSO to 20mM.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Momelotinib (CYT387), ATP-competitve JAK 1/2 selective inhibitor -
Description
Potent ATP-competitve JAK 1/2 selective inhibitor -
Alternative names
- CYT387
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Biological description
Potent ATP-competitive JAK 1/2 selective inhibitor (IC50 values are 11, 18 and 155 nM for JAK1, JAK2 and JAK3 respectively). Shows antiproliferative effects (IC50 = 4 μM, IL-3 stimulated Ba/F3 cells). Shows antitumor effects in vivo. -
Purity
> 95% -
CAS Number
1056634-68-4 -
Chemical structure
