MLN-4924, NEDD8-activating enzyme inhibitor (ab216470)
Key features and details
- Potent, selective NEDD8-activating enzyme inhibitor
- CAS Number: 905579-51-3
- Purity: > 98%
- Soluble in DMSO to 20 mM
- Source: Synthetic
Overview
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Product name
MLN-4924, NEDD8-activating enzyme inhibitor -
Description
Potent, selective NEDD8-activating enzyme inhibitor -
Alternative names
- MLN 4924
- MLN4924
- Pevonedistat
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Purity
> 98% -
CAS Number
905579-51-3 -
Chemical structure
Properties
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Chemical name
((1S,2S,4R)-4-(4-(((S)-2,3-Dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate -
Molecular weight
443.53 -
Molecular formula
C21H25N5O4S -
PubChem identifier
16720766 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 20 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC2=CC=CC=C2[C@H]1NC3=NC=NC4=C3C=CN4[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N -
Source
Synthetic
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Research areas
