ML 141, Cdc42 GTPase inhibitor (ab145603)
Key features and details
- Selective, cell-permeable, reversible, non-competitive Cdc42 GTPase inhibitor
- CAS Number: 71203-35-5
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
ML 141, Cdc42 GTPase inhibitor -
Description
Selective, cell-permeable, reversible, non-competitive Cdc42 GTPase inhibitor -
Biological description
Selective, cell-permeable, reversible, non-competitive Cdc42 GTPase inhibitor (IC50 = 2.6 μM). Shows antiproliferative effects. Shows anticonvulsant effects in vivo. -
Purity
> 98% -
CAS Number
71203-35-5 -
Chemical structure
Properties
-
Chemical name
4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide -
Molecular weight
407.49 -
Molecular formula
C22H21N3O3S -
PubChem identifier
2950007 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4 -
Source
Synthetic
-
Research areas
