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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

MIRA-1, p53 inducer (ab145862)

Price and availability

254 630 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Novel, nontoxic and selective p53 inducer
  • CAS Number: 72835-26-8
  • Purity: > 99%
  • Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    MIRA-1, p53 inducer
  • Description

    Novel, nontoxic and selective p53 inducer
  • Biological description

    Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

  • Purity

    > 99%
  • CAS Number

    72835-26-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
  • Molecular weight

    183.16
  • Molecular formula

    C8H9NO4
  • PubChem identifier

    227681
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC(=O)OCN1C(=O)C=CC1=O
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • DNA Damage Response
    • Other
    • Signal Transduction
    • Metabolism
    • Alcohol metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Alcohol metabolism

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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