Mibefradil dihydrochloride, Ca2+ channel blocker (ab120343)
Key features and details
- Ca2+ channel blocker
- CAS Number: 116666-63-8
- Purity: > 98%
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mibefradil dihydrochloride, Ca2+ channel blocker -
Description
Ca2+ channel blocker -
Biological description
Ca2+ channel blocker. Shows moderate selectivity for T-type channels (IC50 values are 2.7 and 18.6 μM for T-type and L-type respectively). Shows antihypertensive effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
116666-63-8 -
Chemical structure
Properties
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Chemical name
(1S,2S)-2-[2-[[3-(1H-Benzimidazol-2yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetate dihydrochloride -
Molecular weight
568.56 -
Molecular formula
C29H38FN3O3.2HCl -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.CC(C)[C@H]4c5ccc(F)cc5CC[C@]4(OC(=O)C1CC1)CCN(C)CCCc2nc3ccccc3n2 -
Source
Synthetic
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Research areas
