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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

M344, HDAC inhibitor (ab141401)

Key features and details

  • HDAC inhibitor. Shows selectivity for HDAC6.
  • CAS Number: 251456-60-7
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    M344, HDAC inhibitor
  • Description

    HDAC inhibitor. Shows selectivity for HDAC6.
  • Biological description

    HDAC inhibitor (IC50 = 100 nM). Shows selectivity for HDAC6. Inhibits growth of various cancer cells. Apoptosis inducer.
  • Purity

    > 98%
  • CAS Number

    251456-60-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Molecular weight

    307.39
  • Molecular formula

    C16H25N3O3
  • PubChem identifier

    3994
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Cytokines
    • Other
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Immunology
    • Adaptive Immunity
    • MHC
    • Class I
    • Immunology
    • Innate Immunity
    • Cytokines
    • Interferons
    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors
    • Stem Cells
    • Signaling Pathways
    • Wnt
    • HDACs
    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • HDACs
    • Class I
    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • HDACs
    • Class II / Hda1 Class
    • Cancer
    • Tumor immunology
    • Cytokines
    • Interferons
    • Cancer
    • Oncoproteins/suppressors
    • Tumor suppressors
    • Other
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Other
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Metabolism of lipids and lipoproteins
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Hormone biosynthesis
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism
    • Metabolism
    • Pathways and Processes
    • Endocrine metabolism
    • Hormone biosynthesis
    • Biochemicals
    • Pharmacology
    • Signaling
    • Epigenetics
    • Histone Deacetylases (HDAC)
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Deacetylase
    • Histone Deacetylase (HDAC)
    • HDAC6
    • Biochemicals
    • Research Area
    • Cancer
    • Epigenetics
    • Histone Deacetylases (HDAC)
    • Biochemicals
    • Research Area
    • Epigenetics
    • Histone Deacetylases (HDAC)

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