Loratidine, H1 receptor antagonist (ab120766)
Key features and details
- H1 receptor antagonist
- CAS Number: 79794-75-5
- Purity: > 99%
- Soluble in DMSO to 25 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Loratidine, H1 receptor antagonist -
Description
H1 receptor antagonist -
Alternative names
- Loratadine
- SCH 29851
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Biological description
H1 receptor antagonist (Ki values are 16 nM for H1 and 2-10 μM for M1-5 receptors). Antiallergenic activities. Orally active yet centrally inactive.
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Purity
> 99% -
CAS Number
79794-75-5 -
Chemical structure
Properties
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Chemical name
4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester -
Molecular weight
382.89 -
Molecular formula
C22H23ClN2O2 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
