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Immunology Innate Immunity Macrophage / Inflamm.

Leukotriene B4, Leukotriene B4, BLT1 and BLT2 receptor agonist (ab141686)

Key features and details

  • Potent chemoattractant. Leukotriene B4, BLT1 and BLT2 receptor agonist.
  • CAS Number: 71160-24-2
  • Purity: > 99%
  • Supplied in ethanol (1 ml)
  • Form / State: Liquid
  • Source: Synthetic

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Overview

  • Product name

    Leukotriene B4, Leukotriene B4, BLT1 and BLT2 receptor agonist
  • Description

    Potent chemoattractant. Leukotriene B4, BLT1 and BLT2 receptor agonist.
  • Biological description

    Potent chemoattractant (EC50 = 300 nM). Also acts as a leukotriene B4, BLT1 and BLT2 receptor agonist (Kd values are 1.2 and 23 nM, respectively). A lipid derivative of arachidonic acid. Proinflammatory mediator in vivo.
  • Purity

    > 99%
  • CAS Number

    71160-24-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxyicosa-6,8,10,14-tetraenoic acid
  • Molecular weight

    336.50
  • Molecular formula

    C20H32O4
  • PubChem identifier

    5280492
  • Storage instructions

    Store at -80°C.
  • Solubility overview

    Supplied in ethanol (1 ml)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Other
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Immunology
    • Innate Immunity
    • Cytokines
    • Other
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Leukotriene & Related
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Prostaglandins
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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