L-alpha-Phosphatidylinositol-3,4,5-trisphosphate sodium salt, PKC delta, epsilon and eta activator (ab145221)
Key features and details
- Ca2+-insensitive PKC δ, ε and η activator
- CAS Number:
- Purity: > 98%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
L-alpha-Phosphatidylinositol-3,4,5-trisphosphate sodium salt, PKC delta, epsilon and eta activator -
Description
Ca2+-insensitive PKC δ, ε and η activator -
Alternative names
- 1,2-Dipalmitoyl-sn-glycero-3-phospho-1-D-myo-inositol-3,4,5-trisphosphate
- PtdIns(3,4,5)P3
-
Biological description
Activates Ca2+-insensitive PKC isotypes δ, ε and η in vitro. Binds to the general receptor for phosphoinositide-1 (GRP1) protein through a plekstrin homology (PH) domain.
-
Purity
> 98% -
Chemical structure
Properties
-
Chemical name
1,2-Dipalmitoyl-sn-glycero-3-phospho-1-D-myo-inositol-3,4,5-trisphosphate sodium salt -
Molecular weight
1204.80 -
Molecular formula
C41H75Na7O22P4 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic