Jasplakinolide, Actin polymerization and stabilization inducer (ab141409)
Key features and details
- Actin polymerization and stabilization inducer. Cell-permeable.
- CAS Number: 102396-24-7
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Jaspis splendens
Overview
-
Product name
Jasplakinolide, Actin polymerization and stabilization inducer -
Description
Actin polymerization and stabilization inducer. Cell-permeable. -
Biological description
Cell-permeable actin polymerization and stabilization inducer. Potent antiproliferative activity (IC50 = 15 nM). Antitumor and antifungal agent. Active in vitro.
-
Purity
> 95% -
CAS Number
102396-24-7 -
Chemical structure
Properties
-
Chemical name
Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-
trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl] -
Molecular weight
709.68 -
Molecular formula
C36H45BrN4O6 -
PubChem identifier
6436289 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C[C@@H]\1C[C@@H](OC(=O)C[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](C/C(=C1)/C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C -
Source
Jaspis splendens
-
Research areas