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Signal Transduction Protein Phosphorylation Ser / Thr Phosphatases

IQ-1, Wnt pathway activator (ab142079)

Key features and details

  • Cell-permeable Wnt pathway activator
  • CAS Number: 331001-62-8
  • Purity: > 95%
  • Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    IQ-1, Wnt pathway activator
  • Description

    Cell-permeable Wnt pathway activator
  • Biological description

    Cell-permeable Wnt pathway activator. Targets PR72/130 subunit of PP2A. Maintains ESC pluripotency when co-administered with Wnt3a in vitro. Active in vivo.
  • Purity

    > 95%
  • CAS Number

    331001-62-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[(4-Acetylphenyl)diazenyl]-2-(3,3-dimethyl-2,4-dihydro-1H-isoquinolin-1-yl)acetamide
  • Molecular weight

    362.42
  • Molecular formula

    C21H22N4O2
  • PubChem identifier

    11152734
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Phosphatases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phosphatase
    • PP1 & PP2A
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • PI3K/Akt signaling
    • PP1 & PP2A
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Wnt signaling
    • Activators
    • Biochemicals
    • Pharmacology
    • Signaling
    • Stem Cells
    • Wnt signaling

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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