Ipatasertib (GDC-0068) (ab273621)
Key features and details
- Selective Akt1/2/3 inhibitor
- CAS Number: 1001264-89-6
- Purity: >= 98%
Soluble in DMSO to 50 mM
- Source: Synthetic
Overview
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Product name
Ipatasertib (GDC-0068) -
Description
Selective Akt1/2/3 inhibitor -
Biological description
Selective Akt1/2/3 inhibitor (IC50 = 5 nM, 18 nM and 8 nM, respectively). Selective for Akt over PKA (620-fold). ATP-competitive. Antitumor activity in vitro and in vivo.
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Purity
>= 98% -
CAS Number
1001264-89-6 -
Chemical structure
Properties
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Chemical name
(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone
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Molecular weight
458.00 -
Molecular formula
C24H32ClN5O2 -
PubChem identifier
24788740 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O -
Source
Synthetic
Images
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Chemical Structure - Ipatasertib (GDC-0068) (ab273621)
Chemical structure of Ipatasertib (GDC-0068), 1001264-89-6
