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Imperatorin, Cyclin D1 inhibitor (ab143498)

Key features and details

  • Cyclin D1 inhibitor
  • CAS Number: 482-44-0
  • Purity: > 98%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Imperatorin, Cyclin D1 inhibitor
  • Description

    Cyclin D1 inhibitor
  • Biological description

    Cyclin D1 inhibitor. Induces cell cycle arrest at G1. Activates caspase 9 and induces apoptosis. Inhibits HIV-1 replication. Weak TRPV1 agonist (EC50 = 13 μM). Shows antiproliferative effects. Shows analgesic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    482-44-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    9-(3-Methylbut-2-enoxy)furo[3,2-g]chromen-7-one
  • Molecular weight

    270.28
  • Molecular formula

    C16H14O4
  • PubChem identifier

    10212
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cholesterol Metabolism
    • Neuroscience
    • Sensory System
    • Visual system
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Signal Transduction
    • Metabolism
    • Alcohol metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Cyclin-dependent kinase
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Cholesterol Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Alcohol metabolism
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Cyclin-dependent kinase
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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