Ilimaquinone, Cytoplasmic microtubule inhibitor (ab141625)
Key features and details
- Cytoplasmic microtubule inhibitor. Disrupts Golgi membranes.
- CAS Number: 71678-03-0
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ilimaquinone, Cytoplasmic microtubule inhibitor -
Description
Cytoplasmic microtubule inhibitor. Disrupts Golgi membranes. -
Biological description
Induces depolymerisation of cytoplasmic microtubules. Induces a reversible vesiculation of Golgi membranes blocking downstream protein transport. Inhibitor of gap junction communications. Cell-permeable. Anti-inflammatory and anticancer activity. -
Purity
> 98% -
CAS Number
71678-03-0 -
Chemical structure
Properties
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Chemical name
3-[[(1R,2S,4aS,8aS)-1,2,4a-Trimethyl-5-methylidene-3,4,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl]-2-hydroxy-5-methoxycyclohexa-2,5-diene-1,4-dione -
Molecular weight
358.50 -
Molecular formula
C22H30O4 -
PubChem identifier
72291 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C -
Source
Synthetic
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Research areas
