IC 261, CK1delta and CK1epsilon inhibitor (ab145189)
Key features and details
- Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor.
- CAS Number: 186611-52-9
- Purity: > 99%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IC 261, CK1delta and CK1epsilon inhibitor -
Description
Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor. -
Biological description
Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor. Induces cell cycle arrest and apoptosis. Selectively inhibits tumor cells growth. Shows antitumor effects in vivo.
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Purity
> 99% -
CAS Number
186611-52-9 -
Chemical structure
Properties
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Chemical name
(3Z)-1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one -
Molecular weight
311.33 -
Molecular formula
C18H17NO4 -
PubChem identifier
5353678 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC -
Source
Synthetic
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Research areas
