Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor (ab141566)
Key features and details
- Insulin receptor tyrosine kinase inhibitor
- CAS Number: 120943-99-9
- Purity: > 98%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA), Insulin receptor tyrosine kinase inhibitor -
Description
Insulin receptor tyrosine kinase inhibitor -
Biological description
Insulin receptor tyrosine kinase inhibitor (IC50 = 100 µM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Membrane impermeable (membrane permeable analog available ab141567).
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Purity
> 98% -
CAS Number
120943-99-9 -
Chemical structure
Properties
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Chemical name
[Hydroxy(naphthalen-2-yl)methyl]phosphonic acid -
Molecular weight
238.20 -
Molecular formula
C11H11O4P -
PubChem identifier
129317 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C2C=C(C=CC2=C1)C(O)P(=O)(O)O -
Source
Synthetic
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Research areas
