Astana Biomed Group, an authorized Abcam distributor in Central Asia

Human FLT3 (CD135) knockout HeLa cell pellet (ab279172)

Overview

  • Product name

    Human FLT3 (CD135) knockout HeLa cell pellet
    See all Flt3 / CD135 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 2 bp insertion in exon5.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Receptor for the FL cytokine. Has a tyrosine-protein kinase activity.

  • Tissue specificity

    Bone marrow cells.

  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 protein kinase domain.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Alternative names

    • CD 135
    • CD135
    • CD135 antigen
    • Fetal liver kinase 2
    • FL cytokine receptor
    • Flk 2
    • Flk2
    • Flt 3
    • FLT-3
    • Flt3
    • FLT3_HUMAN
    • FMS like tyrosine kinase 3
    • Fms related tyrosine kinase 3
    • Fms-like tyrosine kinase 3
    • Growth factor receptor tyrosine kinase type III
    • Ly-72
    • OTTHUMP0000004234
    • Receptor type tyrosine protein kinase FLT3
    • Stem cell tyrosine kinase 1
    • Stk 1
    • STK-1
    • Stk1
    • Tyrosine protein kinase receptor FLT3
    • Tyrosine-protein kinase receptor FLT3
    see all

Properties

Images

  • Sanger Sequencing - Human FLT3 (CD135) knockout HeLa cell pellet (ab279172)
    Sanger Sequencing - Human FLT3 (CD135) knockout HeLa cell pellet (ab279172)
    Homozygous: 2 bp insertion in exon5

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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