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Immunology Adaptive Immunity T Cells CD

Human CD160 knockout HeLa cell pellet (ab279160)

Price and availability

670 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Human CD160 knockout HeLa cell pellet (ab279160)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

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Overview

  • Product name

    Human CD160 knockout HeLa cell pellet
    See all CD160 kits
  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa
  • Organism

    Human
  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 1 bp deletion in exon3 and 1 bp insertion in exon3.
  • Passage number

  • Knockout validation

    Sanger Sequencing
  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

  • Storage instructions

    Store at -80°C. Please refer to protocols.
  • Components 1 kit
    Human CD160 knockout HeLa cell pellet 1 vial
    Human wild-type HeLa cell pellet 1 vial
  • Research areas

    • Immunology
    • Adaptive Immunity
    • T Cells
    • CD
    • Immunology
    • Immunoglobulins
    • Receptors
    • Immunology
    • Innate Immunity
    • NK Cells
    • Cardiovascular
    • Angiogenesis
    • Endothelial Cell Markers
  • Cell type

    epithelial
  • Disease

    Adenocarcinoma
  • Gender

    Female
  • STR Analysis

    Amelogenin X D5S818: 11, 12 D13S317: 12, 13.3 D7S820: 8, 12 D16S539: 9, 10 vWA: 16, 18 TH01: 7 TPOX: 8,12 CSF1PO: 9, 10

Target

  • Function

    Receptor showing broad specificity for both classical and non-classical MHC class I molecules.
  • Tissue specificity

    Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.
  • Sequence similarities

    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession O95971 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • BY55
    • BY55_HUMAN
    • CD160
    • CD160 antigen
    • CD160 antigen [Precursor]
    • CD160 delta Ig
    • CD160 molecule
    • CD160 transmembrane isoform
    • FLJ46513
    • Natural killer cell receptor BY55
    • Natural killer cell receptor, immunoglobulin superfamily member
    • NK1
    • NK28
    see all

Properties

  • Storage instructions

    Store at -80°C. Please refer to protocols.
  • Components 1 kit
    Human CD160 knockout HeLa cell pellet 1 vial
    Human wild-type HeLa cell pellet 1 vial
  • Research areas

    • Immunology
    • Adaptive Immunity
    • T Cells
    • CD
    • Immunology
    • Immunoglobulins
    • Receptors
    • Immunology
    • Innate Immunity
    • NK Cells
    • Cardiovascular
    • Angiogenesis
    • Endothelial Cell Markers
  • Cell type

    epithelial
  • Disease

    Adenocarcinoma
  • Gender

    Female
  • STR Analysis

    Amelogenin X D5S818: 11, 12 D13S317: 12, 13.3 D7S820: 8, 12 D16S539: 9, 10 vWA: 16, 18 TH01: 7 TPOX: 8,12 CSF1PO: 9, 10

Images

  • Sanger Sequencing - Human CD160 knockout HeLa cell pellet (ab279160)
    Sanger Sequencing - Human CD160 knockout HeLa cell pellet (ab279160)

    Allele-1: 1 bp deletion in exon3

     

  • Sanger Sequencing - Human CD160 knockout HeLa cell pellet (ab279160)
    Sanger Sequencing - Human CD160 knockout HeLa cell pellet (ab279160)

    Allele-2: 1 bp insertion in exon3

     

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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