Astana Biomed Group, an authorized Abcam distributor in Central Asia

Human BMP2 knockout HeLa cell pellet (ab279176)

Overview

  • Product name

    Human BMP2 knockout HeLa cell pellet
    See all BMP2 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 17 bp deletion in exon 2 and Insertion of the selection cassette in exon 2.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Induces cartilage and bone formation.

  • Tissue specificity

    Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

  • Sequence similarities

    Belongs to the TGF-beta family.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Alternative names

    • BDA2
    • BMP-2
    • BMP-2A
    • Bmp2
    • BMP2_HUMAN
    • BMP2A
    • Bone morphogenetic protein 2
    • Bone morphogenetic protein 2A
    see all

Properties

Images

  • Sanger Sequencing - Human BMP2 knockout HeLa cell pellet (ab279176)
    Sanger Sequencing - Human BMP2 knockout HeLa cell pellet (ab279176)

    Allele-1: 17 bp deletion in exon 2

     

  • Sanger Sequencing - Human BMP2 knockout HeLa cell pellet (ab279176)
    Sanger Sequencing - Human BMP2 knockout HeLa cell pellet (ab279176)

    Allele-2: Insertion of the selection cassette in exon 2

     

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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