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Cancer Invasion/microenvironment Hypoxia HIF

GW1929, PPARgamma agonist (ab142213)

Key features and details

  • Potent, selective PPARγ agonist
  • CAS Number: 196808-24-9
  • Purity: > 98%
  • Soluble in water to 100 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    GW1929, PPARgamma agonist
  • Description

    Potent, selective PPARγ agonist
  • Biological description

    Potent, selective PPARγ agonist (EC50 = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    196808-24-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-2-(2-Benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid
  • Molecular weight

    495.57
  • Molecular formula

    C30H29N3O4
  • PubChem identifier

    6518171
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Hypoxia
    • HIF
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Opioid Receptors
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cytochromes
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • HLH / Leucine Zipper
    • HLH
    • Epigenetics and Nuclear Signaling
    • Cardiovascular/Immune
    • Hypoxia
    • HIF
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Stem Cells
    • Mesenchymal Stem Cells
    • Adipogenesis
    • Cancer
    • Invasion/microenvironment
    • Hypoxia
    • HIF
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nuclear Receptors
    • PPAR
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Nucleotide metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes
    • Metabolism
    • Types of disease
    • Obesity
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • Transcription factors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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