GppNHp, Non-hydrolyzable GTP analog (ab146659)
Key features and details
- Non-hydrolyzable GTP analog
- CAS Number: 64564-03-0
- Purity: > 95%
Soluble in water to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GppNHp, Non-hydrolyzable GTP analog -
Description
Non-hydrolyzable GTP analog -
Biological description
Non-hydrolyzable GTP analog. Has an amine group in place of an oxygen atom. Potent adenylate cyclase stimulator. Binds tightly to G-protein in the presence of Mg2+. Forms stable Ras complexes. -
Purity
> 95% -
CAS Number
64564-03-0 -
Chemical structure
Properties
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Chemical name
[[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate tetralithium
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Molecular weight
545.93 -
Molecular formula
C10H13Li4N6O13P3 -
PubChem identifier
136494784 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 75 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O)N=C(NC2=O)N -
Source
Synthetic
