Glabridin, Antiproliferative agent (ab143625)
Key features and details
- Antiproliferative agent
- CAS Number: 59870-68-7
- Purity: > 98%
- Soluble in ethanol and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Glabridin, Antiproliferative agent -
Description
Antiproliferative agent -
Biological description
Antiproliferative agent. Inhibits melanogenesis. Induces apoptosis through caspase 3, 8, and 9 activation and PARP cleavage. Activates ERK1/2, p38 MAPK and JNK1/2. Shows estrogenic, neuroprotective, depigmenting and antitumor effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
59870-68-7 -
Chemical structure
Properties
-
Chemical name
4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol -
Molecular weight
324.37 -
Molecular formula
C20H20O4 -
PubChem identifier
124052 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1(C=CC2=C(O1)C=CC3=C2OCC(C3)C4=C(C=C(C=C4)O)O)C -
Source
Synthetic
-
Research areas
