Gap 26, gap junction blocking peptide (ab269702)
Key features and details
- Gap junction blocking peptide
- CAS Number: 197250-15-0
- Soluble in DMSO to 50 mM with ultrasonic and warming and in water to 100 mM with ultrasonic
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Gap 26, gap junction blocking peptide -
Description
Gap junction blocking peptide -
Biological description
Gap junction blocking peptide. Connexin mimetic corresponding to residues 63-75 of Connexin 43. Inhibits IP3-induced release of ATP. Attenuates arterial smooth muscle contractile activity (IC50 = 28.4 μM). Primary inhibitory effect likely to be on connexin hemichannels.
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CAS Number
197250-15-0 -
Chemical structure
Properties
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Molecular weight
1550.79 -
Molecular formula
C70H107N19O19S -
Sequence
VCYDKSFPISHVR -
PubChem identifier
25088334 -
Storage instructions
Shipped at Room Temperature. Store at -20°C long term. -
Solubility overview
Soluble in DMSO to 50 mM with ultrasonic and warming and in water to 100 mM with ultrasonic -
Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CS)NC(=O)[C@H](C(C)C)N -
Source
Synthetic
Images
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Chemical Structure - Gap 26, gap junction blocking peptide (ab269702)
Chemical structure of Gap 26, gap junction blocking peptide, 197250-15-0