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Neuroscience Neurology process Neurodegenerative disease Alzheimer's disease Proteases

Gabexate mesylate, General serine protease inhibitor (ab141167)

Price and availability

257 980 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • General serine protease inhibitor
  • CAS Number: 56974-61-9
  • Purity: > 99%
  • Soluble in water to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Gabexate mesylate, General serine protease inhibitor
  • Description

    General serine protease inhibitor
  • Alternative names

    • FOY
  • Biological description

    General serine protease inhibitor (Ki values are 3.4 nM, 5, 1.8 µM and 2.6 mM at tryptase, thrombin, tyrpsin and kallikrein serine proteases respectively). Additionally inhibits nitric oxide synthase. Displays antithrombotic activity and antitumor effect. Active in vivo.

  • Purity

    > 99%
  • CAS Number

    56974-61-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester mathanesulfonate
  • Molecular weight

    417.48
  • Molecular formula

    C16H23N3O4.CH3SO3H
  • PubChem identifier

    6604561
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=C(Oc1ccc(cc1)C(=O)OCC)CCCCCNC(=N)N.CS(=O)(=O)O
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Alzheimer's disease
    • Proteases
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cytochromes
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • Kallikreins
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • Kallikreins
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Estrogen
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Serine protease
    • Kallikreins
    • Cancer
    • Tumor biomarkers
    • Receptors
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
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    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Protease
    • General
    • Inhibitors

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