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Immunology Innate Immunity Macrophage / Inflamm.

Flurbiprofen, COX inhibitor NSAID (ab142877)

Key features and details

  • Potent COX inhibitor. NSAID.
  • CAS Number: 5104-49-4
  • Purity: > 98%
  • Soluble in ethanol to 50 mM and in DMSO to100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Flurbiprofen, COX inhibitor NSAID
  • Description

    Potent COX inhibitor. NSAID.
  • Biological description

    Potent COX inhibitor (IC50 values are 0.1 and 0.4 μM for COX-1 and COX-2 respectively). NSAID. Shows analgesic, anti-inflammatory and antipyretic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    5104-49-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(3-Fluoro-4-phenylphenyl)propanoic acid
  • Molecular weight

    244.26
  • Molecular formula

    C15H13FO2
  • PubChem identifier

    3394
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 50 mM and in DMSO to100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Platelets
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cholesterol Metabolism
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Prostaglandins
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Signal Transduction
    • Metabolism
    • Energy Metabolism
    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • Channels
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cancer
    • Tumor biomarkers
    • Other
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    • Atherosclerosis
    • Lipoprotein metabolism
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    • Cancer Metabolism
    • Metabolic signaling pathway
    • Hormone biosynthesis
    • Biochemicals
    • Product Range
    • New
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    • Cyclooxygenase
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    • Energy Metabolism
    • Metabolism
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    • Redox metabolism
    • Oxidative stress
    • Metabolism
    • Pathways and Processes
    • Endocrine metabolism
    • Hormone biosynthesis
    • Metabolism
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