FC 131, CXCR4 activation inhibitor (ab230363)
Key features and details
- An inhibitor of CXCR4 activation
- CAS Number: 606968-52-9
- Purity: > 95%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
FC 131, CXCR4 activation inhibitor -
Description
An inhibitor of CXCR4 activation -
Biological description
FC 131 is an inhibitor of CXCR4 activation by SDF-
1 (IC50 = 4.5 nM). It also blocks HIV- induced cytopathogenicity (EC50 = 73 nM). FC 131 derivatives can be used for imaging CXCR4 in functional studies. -
Purity
> 95% -
CAS Number
606968-52-9 -
Chemical structure
Properties
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Molecular weight
729.83 -
Molecular formula
C36H47N11O6 -
Sequence
XGYRR (Modifications: Cyclic peptide, X = 2-Nal, Tyr-3 = D-Tyr] -
PubChem identifier
5275848 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(NCC(N[C@@H]1CC2=CC=C(O)C=C2)=O)[C@@H](NC([C@@H](NC([C@@H](NC1=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC3=CC(C=CC=C4)=C4C=C3 -
Source
Synthetic
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Research areas